Insulin and IGF-1 elicit robust transcriptional regulation to modulate autophagy in astrocytes

Insulin and IGF-1 elicit robust transcriptional regulation to modulate autophagy in astrocytes

Objective: Insulin is a principal metabolic hormone. It regulates a plethora of metabolic pathways in peripheral tissues. The highly homologous insulin-like growth factor 1 (IGF-1), on the other hand, is important for development and growth. Recent studies have shown that insulin and IGF-1 signaling...

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Bibliographic Details
Main Authors: Shawn J. Geffken, Sohyun Moon, Catherine O. Smith, Sharon Tang, Hiu Ham Lee, Kevin Lewis, Chun Wa Wong, Yuan Huang, Qian Huang, Ying-Tao Zhao, Weikang Cai
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Metabolism
Subjects:
Insulin
IGF-1
Astrocytes
Transcription
Autophagy
Proteostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822002162

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http://www.sciencedirect.com/science/article/pii/S2212877822002162

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