The Role of HIF-1α in Bone Regeneration: A New Direction and Challenge in Bone Tissue Engineering

The process of repairing significant bone defects requires the recruitment of a considerable number of cells for osteogenesis-related activities, which implies the consumption of a substantial amount of oxygen and nutrients. Therefore, the limited supply of nutrients and oxygen at the defect site is...

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Bibliographic Details
Main Authors: Jiaqian You, Manxuan Liu, Minghui Li, Shaobo Zhai, Sezhen Quni, Lu Zhang, Xiuyu Liu, Kewen Jia, Yidi Zhang, Yanmin Zhou
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/9/8029