Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases

Development of Novel Patient-Derived Xenografts from Breast Cancer Brain Metastases

Brain metastases are an increasing burden among breast cancer patients, particularly for those with HER2+ and triple negative (TN) subtypes. Mechanistic insight into the pathophysiology of brain metastases and preclinical validation of therapies has relied almost exclusively on intracardiac injectio...

Descripció completa

Dades bibliogràfiques
Autors principals: María J. Contreras-Zárate, D. Ryan Ormond, Austin E. Gillen, Colton Hanna, Nicole L. Day, Natalie J. Serkova, Britta M. Jacobsen, Susan M. Edgerton, Ann D. Thor, Virginia F. Borges, Kevin O. Lillehei, Michael W. Graner, Peter Kabos, Diana M. Cittelly
Format: Article
Idioma:English
Publicat: Frontiers Media S.A. 2017-11-01
Col·lecció:Frontiers in Oncology
Matèries:
patient-derived xenograft
brain metastases models
breast cancer
brain colonization
triple negative
HER2+
Accés en línia:http://journal.frontiersin.org/article/10.3389/fonc.2017.00252/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00252/full

Ítems similars