Generation of a Novel Nucleic Acid-Based Reporter System To Detect Phenotypic Susceptibility to Antibiotics in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
ABSTRACT We designed, constructed, and evaluated a prototype novel reporter system comprised of two functional cassettes: (i) the SP6 RNA polymerase gene under transcriptional control of a promoter active in mycobacteria and (ii) the consensus SP6 polymerase promoter that directs expression of an ot...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2012-05-01
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Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.00312-11 |