Generation of a Novel Nucleic Acid-Based Reporter System To Detect Phenotypic Susceptibility to Antibiotics in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT We designed, constructed, and evaluated a prototype novel reporter system comprised of two functional cassettes: (i) the SP6 RNA polymerase gene under transcriptional control of a promoter active in mycobacteria and (ii) the consensus SP6 polymerase promoter that directs expression of an ot...

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Bibliographic Details
Main Authors: Matthew C. Mulvey, Katherine A. Sacksteder, Leo Einck, Carol A. Nacy
Format: Article
Language:English
Published: American Society for Microbiology 2012-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00312-11