Roles of cMyBP-C phosphorylation on cardiac contractile dysfunction in db/db mice

Roles of cMyBP-C phosphorylation on cardiac contractile dysfunction in db/db mice

Type 2 diabetes mellitus (T2DM) is a metabolic disease and comorbidity associated with several conditions, including cardiac dysfunction leading to heart failure with preserved ejection fraction (HFpEF), in turn resulting in T2DM-induced cardiomyopathy (T2DM-CM). However, the molecular mechanisms un...

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Bibliographic Details
Main Authors: Darshini A. Desai, Akhil Baby, Kalyani Ananthamohan, Lisa C. Green, Mohammed Arif, Brittany C. Duncan, Mohit Kumar, Rohit R. Singh, Sheryl E. Koch, Sankar Natesan, Jack Rubinstein, Anil G. Jegga, Sakthivel Sadayappan
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Journal of Molecular and Cellular Cardiology Plus
Subjects:
cMyBP-C
Diabetes
HFpEF
MYBPC3
Mavacamten
Phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2772976124000151

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http://www.sciencedirect.com/science/article/pii/S2772976124000151

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