ELAC2/RNaseZ-linked cardiac hypertrophy in Drosophila melanogaster

ELAC2/RNaseZ-linked cardiac hypertrophy in Drosophila melanogaster

A severe form of infantile cardiomyopathy (CM) has been linked to mutations in ELAC2, a highly conserved human gene. It encodes Zinc phosphodiesterase ELAC protein 2 (ELAC2), which plays an essential role in the production of mature tRNAs. To establish a causal connection between ELAC2 variants and...

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Bibliographic Details
Main Authors: Ekaterina Migunova, Joanna Theophilopoulos, Marisa Mercadante, Jing Men, Chao Zhou, Edward B. Dubrovsky
Format: Article
Language:English
Published: The Company of Biologists 2021-08-01
Series:Disease Models & Mechanisms
Subjects:
drosophila
cardiomyopathy
elac2
rnase z
ocm
Online Access:http://dmm.biologists.org/content/14/8/dmm048931

Internet

http://dmm.biologists.org/content/14/8/dmm048931

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