Effects of Omalizumab on FcεRI and IgE Expression in Lesional Skin of Bullous Pemphigoid

Effects of Omalizumab on FcεRI and IgE Expression in Lesional Skin of Bullous Pemphigoid

Recent studies suggest an important role of immunoglobulin E (IgE) as an alternative pathogenic pathway in the development of bullous pemphigoid (BP), as the most frequent subepidermal blistering disease of the skin Use of IgE targeted therapies, such as omalizumab, has been shown promising in recen...

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Bibliographic Details
Main Authors: S. Morteza Seyed Jafari, Karolina Gadaldi, Laurence Feldmeyer, Nikhil Yawalkar, Luca Borradori, Christoph Schlapbach
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
bullous pemphigoid
FcεRI
IgE
omalizumab
skin
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01919/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01919/full

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