Release of Tretinoin Solubilized in Microemulsion from Carbopol and Xanthan Gel: In Vitro versus Ex Vivo Permeation Study

Background: Tretinoin (TRE) is, for its anti-comedogenic and comedolytic activity, widely used in the topical treatment of acne vulgaris. The effect lies in the regulation of sebum production and collagen synthesis. The study is devoted to the formulation of dermal gels containing TRE using microemu...

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Bibliographic Details
Main Authors: Miroslava Špaglová, Martina Papadakos, Mária Čuchorová, Desana Matušová
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Polymers
Subjects:
Online Access:https://www.mdpi.com/2073-4360/15/2/329