Elevated Foxp3+ double-negative T cells are associated with disease progression during HIV infection

Elevated Foxp3+ double-negative T cells are associated with disease progression during HIV infection

Persistent immune activation, which occurs during the whole course of HIV infection, plays a pivotal role in CD4+ T cells depletion and AIDS progression. Furthermore, immune activation is a key factor that leads to impaired immune reconstitution after long-term effective antiretroviral therapy (ART)...

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Bibliographic Details
Main Authors: Leidan Zhang, Yuqing Wei, Di Wang, Juan Du, Xinyue Wang, Bei Li, Meiqing Jiang, Mengyuan Zhang, Na Chen, Meiju Deng, Chuan Song, Danying Chen, Liang Wu, Jiang Xiao, Hongyuan Liang, Hongxin Zhao, Yaxian Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
HIV
Foxp3
double-negative T cell
immune activation
immune regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.947647/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.947647/full

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