In <i>Candida glabrata</i>, ERMES Component <i>GEM1</i> Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility

In <i>Candida glabrata</i>, ERMES Component <i>GEM1</i> Controls Mitochondrial Morphology, mtROS, and Drug Efflux Pump Expression, Resulting in Azole Susceptibility

Mitochondrial dysfunction or morphological abnormalities in human pathogenic fungi are known to contribute to azole resistance; however, the underlying molecular mechanisms are unknown. In this study, we investigated the link between mitochondrial morphology and azole resistance in <i>Candida...

Full description

Bibliographic Details
Main Authors: Michiyo Okamoto, Keiko Nakano, Azusa Takahashi-Nakaguchi, Kaname Sasamoto, Masashi Yamaguchi, Miguel Cacho Teixeira, Hiroji Chibana
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Journal of Fungi
Subjects:
ERMES component
<i>GEM1</i>
mitochondrial dynamics
mitochondrial fission
<i>PDR1</i>
<i>CDR1</i>
Online Access:https://www.mdpi.com/2309-608X/9/2/240

Internet

https://www.mdpi.com/2309-608X/9/2/240

Similar Items