Development of pectin nanoparticles through mechanical homogenization for dissolution enhancement of itraconazole

Development of pectin nanoparticles through mechanical homogenization for dissolution enhancement of itraconazole

A simple method to fabricate itraconazole (ITZ)-loaded pectin nanoparticles prepared from nanoemulsion templates is described in this study. Nanoemulsions containing ITZ were prepared by a mechanical homogenization using pectin as emulsifier. After freeze-drying, the morphology, crystallinity state,...

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Bibliographic Details
Main Authors: Kanokporn Burapapadh, Hirofumi Takeuchi, Pornsak Sriamornsak
Format: Article
Language:English
Published: Elsevier 2016-06-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Pectin
Poorly water-soluble drug
Itraconazole
Nanoparticles
Stability
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087615000604

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http://www.sciencedirect.com/science/article/pii/S1818087615000604

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