Endopeptidase-mediated beta lactam tolerance.

In many bacteria, inhibition of cell wall synthesis leads to cell death and lysis. The pathways and enzymes that mediate cell lysis after exposure to cell wall-acting antibiotics (e.g. beta lactams) are incompletely understood, but the activities of enzymes that degrade the cell wall ('autolysi...

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Bibliographic Details
Main Authors: Tobias Dörr, Brigid M Davis, Matthew K Waldor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4401780?pdf=render