Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways

Mucuna pruriens Protects against MPTP Intoxicated Neuroinflammation in Parkinson’s Disease through NF-κB/pAKT Signaling Pathways

Till date, drugs that have been used to manage Parkinson’s disease (PD) have only shown symptomatic relief with several adverse effects besides their inability to prevent neurodegeneration. Neuroinflammation plays an important role in the advancement of PD and can be targeted for its effective treat...

Full description

Bibliographic Details
Main Authors: Sachchida N. Rai, Hareram Birla, Saumitra S. Singh, Walia Zahra, Ravishankar R. Patil, Jyoti P. Jadhav, Mallikarjuna R. Gedda, Surya P. Singh
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson’s disease
neuroinflammation
Mucuna pruriens
tyrosine hydroxylase
MPTP (1-methyl-4-phenyl-1
2
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00421/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00421/full

Similar Items