Novel Dental Anomaly–associated Mutations in WNT10A Protein Binding Sites

Novel Dental Anomaly–associated Mutations in WNT10A Protein Binding Sites

Objective: WNT/β-catenin signaling is initiated by binding of a WNT protein to a Frizzled (FZD) receptor and a co-receptor, low-density lipoprotein (LDL) receptor-related protein 5 or 6 (LRP5/6). The objective of this study was to find the genetic variants responsible for dental anomalies found in 4...

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Bibliographic Details
Main Authors: Piranit Kantaputra, Peeranat Jatooratthawichot, Oranuch Tantachamroon, Kamonporn Nanekrungsan, Worrachet Intachai, Bjorn Olsen, Sissades Tongsima, Chumpol Ngamphiw, James R. Ketudat Cairns
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:International Dental Journal
Subjects:
WNT10A mutation
Frizzled binding site
Dental anomaly
Hypodontia
Dental malformation
Dental defect
Online Access:http://www.sciencedirect.com/science/article/pii/S0020653922000764

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http://www.sciencedirect.com/science/article/pii/S0020653922000764

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