Activating and Attenuating the Amicoumacin Antibiotics

The amicoumacins belong to a class of dihydroisocoumarin natural products and display antibacterial, antifungal, anticancer, and anti-inflammatory activities. Amicoumacins are the pro-drug activation products of a bacterial nonribosomal peptide-polyketide hybrid biosynthetic pathway and have been is...

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Bibliographic Details
Main Authors: Hyun Bong Park, Corey E. Perez, Elena Kim Perry, Jason M. Crawford
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/7/824