The Involvement of the Endogenous Opioid System in the Gastrointestinal Aging in Mice and Humans

The Involvement of the Endogenous Opioid System in the Gastrointestinal Aging in Mice and Humans

Nearly 20% of elderly patients suffer from constipation, but the age-related changes in the gastrointestinal (GI) tract remain insufficiently elucidated. In this study, the alterations within the endogenous opioid system (EOS) as a potential cause of constipation in the elderly were evaluated. The G...

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Bibliographic Details
Main Authors: Agata Szymaszkiewicz, Marcin Talar, Jakub Włodarczyk, Mikołaj Świerczyński, Adrian Bartoszek, Julia Krajewska, Anna Mokrowiecka, Ewa Małecka-Wojciesko, Jakub Fichna, Marta Zielińska
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
aging
constipation
the elderly
endogenous opioid system
opioid receptors
opioids
Online Access:https://www.mdpi.com/1422-0067/23/7/3565

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https://www.mdpi.com/1422-0067/23/7/3565

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