Multiparametric profiling of HER2-enriched extracellular vesicles in breast cancer using Single Extracellular VEsicle Nanoscopy

Multiparametric profiling of HER2-enriched extracellular vesicles in breast cancer using Single Extracellular VEsicle Nanoscopy

Abstract Background Patients with HER2-positive breast cancer can significantly benefit from HER2-directed therapy – such as the monoclonal antibody trastuzumab. However, some patients can develop therapy resistance or change HER2 status. Thus, we urgently need new, noninvasive strategies to monitor...

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Bibliographic Details
Main Authors: Nan Jiang, Andras Saftics, Eugenia Romano, Ima Ghaeli, Cristal Resto, Vanessa Robles, Saumya Das, Kendall Van Keuren-Jensen, Victoria L. Seewaldt, Tijana Jovanovic-Talisman
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Journal of Nanobiotechnology
Subjects:
Single Molecule Localization Microscopy (SMLM)
Single Extracellular VEsicle Nanoscopy (SEVEN)
HER2
Trastuzumab
Breast Cancer
Extracellular vesicles
Online Access:https://doi.org/10.1186/s12951-024-02858-x

Internet

https://doi.org/10.1186/s12951-024-02858-x

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