LTT and HLA testing as diagnostic tools in Spanish vancomycin-induced DRESS cases: A case-control study

LTT and HLA testing as diagnostic tools in Spanish vancomycin-induced DRESS cases: A case-control study

Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe T-cell-mediated off-target adverse reaction. DRESS cases caused by vancomycin have often been reported. The HLA-A*32:01 allele has been associated with genetic susceptibility to vancomycin-induced DRESS in US citizens of Europ...

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Bibliographic Details
Main Authors: Teresa Bellón, Victoria Lerma, Javier Guijarro, Elena Ramírez, Celia Martínez, Carmelo Escudero, Ana M. Fiandor, Ruth Barranco, Manuel de Barrio, Francisco de Abajo, Rosario Cabañas, PIELenRed Study Group
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Pharmacology
Subjects:
drug hypersensitivity
DRESS
HLA
LTT
severe cutaneous adverse reactions
vancomycin
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.959321/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.959321/full

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