Alterations of the Blood-Brain Barrier and Regional Perfusion in Tumor Development: MRI Insights from a Rat C6 Glioma Model.

Angiogenesis and anti-angiogenetic medications play an important role in progression and therapy of glioblastoma. In this context, in vivo characterization of the blood-brain-barrier and tumor vascularization may be important for individual prognosis and therapy optimization.We analyzed perfusion an...

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Bibliographic Details
Main Authors: Monika Huhndorf, Amir Moussavi, Nadine Kramann, Olga Will, Kirsten Hattermann, Christine Stadelmann, Olav Jansen, Susann Boretius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5179246?pdf=render