Cell-cell interactions and fluctuations in the direction of motility promote directed migration of osteoblasts in direct current electrotaxis

Cell-cell interactions and fluctuations in the direction of motility promote directed migration of osteoblasts in direct current electrotaxis

Under both physiological (development, regeneration) and pathological conditions (cancer metastasis), cells migrate while sensing environmental cues in the form of mechanical, chemical or electrical stimuli. In the case of bone tissue, osteoblast migration is essential in bone regeneration. Although...

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Bibliographic Details
Main Authors: Jonathan Edward Dawson, Tina Sellmann, Katrin Porath, Rainer Bader, Ursula van Rienen, Revathi Appali, Rüdiger Köhling
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cell migration
electrotaxis
osteoblasts
computational modeling
collective migration
particle based approach
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.995326/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.995326/full

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