Streptococcus pyogenes Φ1207.3 Is a Temperate Bacteriophage Carrying the Macrolide Resistance Gene Pair mef(A)-msr(D) and Capable of Lysogenizing Different Streptococci

Streptococcus pyogenes Φ1207.3 Is a Temperate Bacteriophage Carrying the Macrolide Resistance Gene Pair mef(A)-msr(D) and Capable of Lysogenizing Different Streptococci

ABSTRACT Streptococcus pyogenes prophage Φ1207.3 (formerly Tn1207.3) carries the mef(A)-msr(D) resistance genes, responsible for type M macrolide resistance. To investigate if Φ1207.3 is a functional bacteriophage, we transferred the element from the original S. pyogenes host in a prophage-free and...

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Bibliographic Details
Main Authors: Francesco Santoro, Gabiria Pastore, Valeria Fox, Marie-Agnes Petit, Francesco Iannelli, Gianni Pozzi
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
temperate phage
lysogenization
Streptococcus pyogenes
Streptococcus pneumoniae
Φ1207.3
mitomycin C
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04211-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.04211-22

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