Integrating end-to-end learning with deep geometrical potentials for ab initio RNA structure prediction

Abstract RNAs are fundamental in living cells and perform critical functions determined by their tertiary architectures. However, accurate modeling of 3D RNA structure remains a challenging problem. We present a novel method, DRfold, to predict RNA tertiary structures by simultaneous learning of loc...

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Bibliographic Details
Main Authors: Yang Li, Chengxin Zhang, Chenjie Feng, Robin Pearce, P. Lydia Freddolino, Yang Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41303-9