Co-Loading of Temozolomide and Curcumin into a Calix[4]arene-Based Nanocontainer for Potential Combined Chemotherapy: Binding Features, Enhanced Drug Solubility and Stability in Aqueous Medium

Co-Loading of Temozolomide and Curcumin into a Calix[4]arene-Based Nanocontainer for Potential Combined Chemotherapy: Binding Features, Enhanced Drug Solubility and Stability in Aqueous Medium

The co-delivery of anticancer drugs into tumor cells by a nanocarrier may provide a new paradigm in chemotherapy. Temozolomide and curcumin are anticancer drugs with a synergistic effect in the treatment of multiform glioblastoma. In this study, the entrapment and co-entrapment of temozolomide and c...

Full description

Bibliographic Details
Main Authors: Rossella Migliore, Nicola D’Antona, Carmelo Sgarlata, Grazia M. L. Consoli
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Nanomaterials
Subjects:
calix[4]arene-based nanoparticle
temozolomide
curcumin
drug delivery
binding interactions
drug combination
Online Access:https://www.mdpi.com/2079-4991/11/11/2930

Internet

https://www.mdpi.com/2079-4991/11/11/2930

Similar Items