Morphologic, phenotypic, and genotypic similarities between primary tumors and corresponding 3D cell cultures grown in a repeatable system—preliminary results

Morphologic, phenotypic, and genotypic similarities between primary tumors and corresponding 3D cell cultures grown in a repeatable system—preliminary results

Abstract Background Three-dimensional (3D) cell cultures are the new frontier for reproducing the tumor micro-environment in vitro. The aims of the study were (1) to establish primary 3D cell cultures from canine spontaneous neoplasms and (2) to demonstrate the morphological, phenotypic and genotypi...

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Bibliographic Details
Main Authors: Luisa Vera Muscatello, Stella Frabetti, Giancarlo Avallone, Francesca Gobbo, Arianna Pasquini, Giulia D’Annunzio, Luciano Pisoni, Laura Marconato, Rossella Terragni, Dario De Biase, Olivia Candini, Giuseppe Sarli
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Veterinary Research
Subjects:
3D cell culture
Dog
Spontaneous Neoplasms
Tumor cells morphology
Immunophenotypes
Genetic profile
Online Access:https://doi.org/10.1186/s12917-023-03834-7

Internet

https://doi.org/10.1186/s12917-023-03834-7

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