Natural Product Alantolactone Targeting AKR1C1 Suppresses Cell Proliferation and Metastasis in Non-Small-Cell Lung Cancer

Natural Product Alantolactone Targeting AKR1C1 Suppresses Cell Proliferation and Metastasis in Non-Small-Cell Lung Cancer

Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer-related deaths, characterized by high invasion and metastasis. Aldo-keto reductase family 1 member C1 (AKR1C1) plays an important role in cancer cell proliferation and metastasis, and has gained attention as an anticancer drug...

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Bibliographic Details
Main Authors: Zhiwen Fu, Shijun Li, Jinmei Liu, Cong Zhang, Chen Jian, Lulu Wang, Yu Zhang, Chen Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
alantolactone
AKR1C1
anticancer
target identification
non-small-cell lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.847906/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.847906/full

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