Good Tumor Response to Chemoradioimmunotherapy in dMMR/MSI-H Advanced Colorectal Cancer: A Case Series

Good Tumor Response to Chemoradioimmunotherapy in dMMR/MSI-H Advanced Colorectal Cancer: A Case Series

PurposeImmune checkpoint blockade has led to a significant improvement of patient survival in metastatic colorectal cancer (CRC) with DNA mismatch repair-deficiency (dMMR)/microsatellite instability-high (MSI-H). However, not all these patients are sensitive to monoimmunotherapy. We firstly presente...

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Bibliographic Details
Main Authors: Chengjing Zhou, Ting Jiang, Yajie Xiao, Qiaoxuan Wang, Zhifan Zeng, Peiqiang Cai, Yongtian Zhao, Zhikun Zhao, Dongfang Wu, Hanqing Lin, Chao Sun, Rong Zhang, Weiwei Xiao, Yuanhong Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Immunology
Subjects:
chemotherapy
radiotherapy
immunotherapy
programmed cell death protein 1 inhibitor
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.784336/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.784336/full

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