Activation of synovial fibroblasts from patients at revision of their metal-on-metal total hip arthroplasty

Activation of synovial fibroblasts from patients at revision of their metal-on-metal total hip arthroplasty

Abstract Background The toxicity of released metallic particles generated in metal-on-metal (MoM) total hip arthroplasty (THA) using cobalt chromium (CoCr) has raised concerns regarding their safety amongst both surgeons and the public. Soft tissue changes such as pseudotumours and metallosis have b...

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Bibliographic Details
Main Authors: Jing Xu, Junyao Yang, Jian Chen, Xiaoli Zhang, Yuanhao Wu, Alister Hart, Agata Nyga, Julia C. Shelton
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Particle and Fibre Toxicology
Subjects:
Cobalt chromium debris
Synovial fibroblast
Inflammation
Fibrosis
Online Access:http://link.springer.com/article/10.1186/s12989-020-00374-y

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http://link.springer.com/article/10.1186/s12989-020-00374-y

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