Cytochrome P450 enzymes: understanding the biochemical hieroglyphs [v1; ref status: indexed, http://f1000r.es/583]
Cytochrome P450 (CYP) enzymes are the primary proteins of drug metabolism and steroid biosynthesis. These crucial proteins have long been known to harbor a cysteine thiolate bound to the heme iron. Recent advances in the field have illuminated the nature of reactive intermediates in the reaction cyc...
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Format: | Article |
Language: | English |
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F1000 Research Ltd
2015-07-01
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Series: | F1000Research |
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Online Access: | http://f1000research.com/articles/4-178/v1 |