Knock-Out of Retrovirus Receptor Gene <i>Tva</i> in the Chicken Confers Resistance to Avian Leukosis Virus Subgroups A and K and Affects Cobalamin (Vitamin B<sub>12</sub>)-Dependent Level of Methylmalonic Acid

Knock-Out of Retrovirus Receptor Gene <i>Tva</i> in the Chicken Confers Resistance to Avian Leukosis Virus Subgroups A and K and Affects Cobalamin (Vitamin B<sub>12</sub>)-Dependent Level of Methylmalonic Acid

The chicken Tva cell surface protein, a member of the low-density lipoprotein receptor family, has been identified as an entry receptor for avian leukosis virus of classic subgroup A and newly emerging subgroup K. Because both viruses represent an important concern for the poultry industry, we intro...

Full description

Bibliographic Details
Main Authors: Anna Koslová, Pavel Trefil, Jitka Mucksová, Veronika Krchlíková, Jiří Plachý, Jakub Krijt, Markéta Reinišová, Dana Kučerová, Josef Geryk, Jiří Kalina, Filip Šenigl, Daniel Elleder, Viktor Kožich, Jiří Hejnar
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
avian leukosis virus subgroups A/K
<i>tva</i>
gene editing in chicken
vitamin B<sub>12</sub>/cobalamin
Online Access:https://www.mdpi.com/1999-4915/13/12/2504

Internet

https://www.mdpi.com/1999-4915/13/12/2504

Similar Items