Conformational Changes in Ff Phage Protein gVp upon Complexation with Its Viral Single-Stranded DNA Revealed Using Magic-Angle Spinning Solid-State NMR

Conformational Changes in Ff Phage Protein gVp upon Complexation with Its Viral Single-Stranded DNA Revealed Using Magic-Angle Spinning Solid-State NMR

Gene V protein (gVp) of the bacteriophages of the Ff family is a non-specific single-stranded DNA (ssDNA) binding protein. gVp binds to viral DNA during phage replication inside host <i>Escherichia coli</i> cells, thereby blocking further replication and signaling the assembly of new pha...

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Bibliographic Details
Main Authors: Smadar Kedem, Roni Rene Hassid, Yoav Shamir, Amir Goldbourt
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
solid-state NMR
fd bacteriophage
DNA binding protein
gVp
protein–DNA interactions
Online Access:https://www.mdpi.com/1999-4915/14/6/1264

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https://www.mdpi.com/1999-4915/14/6/1264

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