Extended-Synaptotagmin 1 Enhances Liver Cancer Progression Mediated by the Unconventional Secretion of Cytosolic Proteins

Extended-Synaptotagmin 1 Enhances Liver Cancer Progression Mediated by the Unconventional Secretion of Cytosolic Proteins

Extended-synaptotagmin 1 (E-Syt1) is an endoplasmic reticulum membrane protein that is involved in cellular lipid transport. Our previous study identified E-Syt1 as a key factor for the unconventional protein secretion of cytoplasmic proteins in liver cancer, such as protein kinase C delta (PKCδ); h...

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Bibliographic Details
Main Authors: Kohji Yamada, Yoshito Hannya, Tsunekazu Oikawa, Ayano Yoshida, Kuniko Katagiri, Saishu Yoshida, Rei Koizumi, Naoko Tago, Yuya Shimoyama, Akira Kawamura, Yuta Mochimaru, Ken Eto, Kiyotsugu Yoshida
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
unconventional secretion
E-Syt1
hepatocellular carcinoma
tumorigenesis
PKCδ
Online Access:https://www.mdpi.com/1420-3049/28/10/4033

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https://www.mdpi.com/1420-3049/28/10/4033

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