Spinal botulinum neurotoxin B: effects on afferent transmitter release and nociceptive processing.

Spinal botulinum neurotoxin B: effects on afferent transmitter release and nociceptive processing.

Botulinum neurotoxin B (BoNT-B) mediates proteolytic cleavage of VAMP I/II (synaptobrevins I/II), which prevents vesicle-membrane fusion and blocks neurotransmitter release. In the present study, we investigated the effects of BoNT-B on neurotransmitter release in vivo from spinal primary afferent s...

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Bibliographic Details
Main Authors: Polly P Huang, Imran Khan, Mohammed S A Suhail, Shelle Malkmus, Tony L Yaksh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084763?pdf=render

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http://europepmc.org/articles/PMC3084763?pdf=render

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