miR-590-5p/Tiam1-mediated glucose metabolism promotes malignant evolution of pancreatic cancer by regulating SLC2A3 stability

miR-590-5p/Tiam1-mediated glucose metabolism promotes malignant evolution of pancreatic cancer by regulating SLC2A3 stability

Abstract Background T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical role in the progression of various malignancies. Glycolysis plays an important role in cancer progression, it is crucial for supplying energ...

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Bibliographic Details
Main Authors: Ying Liu, Aihua Jin, Xianglan Quan, Xionghu Shen, Houkun Zhou, Xingyu Zhao, Zhenhua Lin
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cancer Cell International
Subjects:
Tiam1
Pancreatic cancer
Metastasis
Glucose metabolic reprogramming
miR-590-5p
Online Access:https://doi.org/10.1186/s12935-023-03159-3

Internet

https://doi.org/10.1186/s12935-023-03159-3

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