A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer’s disease and gastrointestinal tract disorders

A cross-trait meta-analysis of several genome-wide association studies suggest that Alzheimer’s disease shares a common genetic basis (including 7 shared loci) and underlying biological pathways with gastrointestinal tract disorders.

Bibliographic Details
Main Authors: Emmanuel O. Adewuyi, Eleanor K. O’Brien, Dale R. Nyholt, Tenielle Porter, Simon M. Laws
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03607-2