Weighted Gene Co-Expression Network Analysis Identifies a Functional Guild and Metabolite Cluster Mediating the Relationship between Mucosal Inflammation and Adherence to the Mediterranean Diet in Ulcerative Colitis

Weighted Gene Co-Expression Network Analysis Identifies a Functional Guild and Metabolite Cluster Mediating the Relationship between Mucosal Inflammation and Adherence to the Mediterranean Diet in Ulcerative Colitis

Diet influences the pathogenesis and clinical course of inflammatory bowel disease (IBD). The Mediterranean diet (MD) is linked to reductions in inflammatory biomarkers and alterations in microbial taxa and metabolites associated with health. We aimed to identify features of the gut microbiome that...

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Bibliographic Details
Main Authors: Jaclyn C. Strauss, Natasha Haskey, Hena R. Ramay, Tarini Shankar Ghosh, Lorian M. Taylor, Munazza Yousuf, Christina Ohland, Kathy D. McCoy, Richard J. M. Ingram, Subrata Ghosh, Remo Panaccione, Maitreyi Raman
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
inflammatory bowel disease
ulcerative colitis
diet
microbiome
metabolomics
weighted gene co-expression analysis (WGCNA)
Online Access:https://www.mdpi.com/1422-0067/24/8/7323

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https://www.mdpi.com/1422-0067/24/8/7323

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