Distinct cervical tissue-adherent and luminal microbiome communities correlate with mucosal host gene expression and protein levels in Kenyan sex workers

Distinct cervical tissue-adherent and luminal microbiome communities correlate with mucosal host gene expression and protein levels in Kenyan sex workers

Abstract Background The majority of studies characterizing female genital tract microbiota have focused on luminal organisms, while the presence and impact of tissue-adherent ectocervical microbiota remain incompletely understood. Studies of luminal and tissue-associated bacteria in the gastrointest...

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Bibliographic Details
Main Authors: Gabriella Edfeldt, Vilde Kaldhusdal, Paulo Czarnewski, Frideborg Bradley, Sofia Bergström, Julie Lajoie, Jiawu Xu, Anna Månberg, Joshua Kimani, Julius Oyugi, Peter Nilsson, Annelie Tjernlund, Keith R. Fowke, Douglas S. Kwon, Kristina Broliden
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Microbiome
Subjects:
Cervix
Ectocervix
Microbiota
16S rRNA gene
Tissue
Tissue-adherent
Online Access:https://doi.org/10.1186/s40168-023-01502-4

Internet

https://doi.org/10.1186/s40168-023-01502-4

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