Stronger T cell immunogenicity of ovalbumin expressed intracellularly in Gram-negative than in Gram-positive bacteria.

This study aimed to clarify whether Gram-positive (G+) and Gram-negative (G-) bacteria affect antigen-presenting cells differently and thereby influence the immunogenicity of proteins they express. Lactobacilli, lactococci and Escherichia coli strains were transformed with plasmids conferring intrac...

Full description

Bibliographic Details
Main Authors: Anna Martner, Sofia Ostman, Samuel Lundin, Carola Rask, Viktor Björnsson, Esbjörn Telemo, L Vincent Collins, Lars Axelsson, Agnes E Wold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23741469/pdf/?tool=EBI