Development of CRISPR Interference (CRISPRi) Platform for Metabolic Engineering of <i>Leuconostoc citreum</i> and Its Application for Engineering Riboflavin Biosynthesis

Development of CRISPR Interference (CRISPRi) Platform for Metabolic Engineering of <i>Leuconostoc citreum</i> and Its Application for Engineering Riboflavin Biosynthesis

<i>Leuconostoc</i><i>citreum</i>, a hetero-fermentative type of lactic acid bacteria, is a crucial probiotic candidate because of its ability to promote human health. However, inefficient gene manipulation tools limit its utilization in bioindustries. We report, for the first...

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Bibliographic Details
Main Authors: Jaewoo Son, Seung Hoon Jang, Ji Won Cha, Ki Jun Jeong
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
lactic acid bacteria
<i>Leuconostoc citreum</i>
CRISPRi
synthetic biology
riboflavin
Online Access:https://www.mdpi.com/1422-0067/21/16/5614

Internet

https://www.mdpi.com/1422-0067/21/16/5614

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