Enhanced anti-hepatoma effect of a novel curcumin analog C086 via solid dispersion technology

The novel curcumin analog C086, previously identified as an oral novel heat shock protein 90 (Hsp90) inhibitor, was found to exhibit anti-hepatoma activity in vitro and in vivo. However, owing to its limited aqueous solubility, the usage of C086 in the clinical application was restricted. This resea...

Full description

Bibliographic Details
Main Authors: Yanping Deng, Chun Chen, Zhifeng Xiao, Xiuwang Huang, Jianhua Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2020.1785051