Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle

Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle

In Duchenne muscular dystrophy (DMD), lack of dystrophin increases the permeability of myofiber plasma membranes to ions and larger macromolecules, disrupting calcium signaling and leading to progressive muscle wasting. Although the biological origin and meaning are unclear, alterations of phosphati...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: William J. Valentine, Sherif A. Mostafa, Suzumi M. Tokuoka, Fumie Hamano, Natsuko F. Inagaki, Joel Z. Nordin, Norio Motohashi, Yoshihiro Kita, Yoshitsugu Aoki, Takao Shimizu, Hideo Shindou
Format: Artykuł
Język:English
Wydane: Frontiers Media S.A. 2022-01-01
Seria:Frontiers in Physiology
Hasła przedmiotowe:
mdx
Duchenne
phospholipid
phosphatidylcholine
oleic acid
muscular dystrophy
Dostęp online:https://www.frontiersin.org/articles/10.3389/fphys.2021.698166/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.698166/full

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