The overexpression of Rps14 in Lgr5+ progenitor cells promotes hair cell regeneration in the postnatal mouse cochlea

The overexpression of Rps14 in Lgr5+ progenitor cells promotes hair cell regeneration in the postnatal mouse cochlea

Sensory hair cells (HCs) in the cochlea cannot regenerate spontaneously in adult mammals after being damaged by external or genetic factors. However, several genes and signaling pathways are reported to induce cochlear HC regeneration at the early neonatal stage. Rps14 encodes a ribosomal protein th...

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Bibliographic Details
Main Authors: Jingru Ai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Mingchen Dai, Yintao Wang, Yuan Zhang, Mengyao Tian, Renjie Chai, Shasha Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-09-01
Series:Engineered Regeneration
Subjects:
Rps14
Lgr5+ progenitor cells
Ectopic hair cells
Regeneration
Proliferation
Trans-differentiation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666138123000361

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http://www.sciencedirect.com/science/article/pii/S2666138123000361

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