An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma

An asparagine metabolism-based classification reveals the metabolic and immune heterogeneity of hepatocellular carcinoma

Abstract Introduction and objectives hepatocellular carcinoma (HCC) is the major form of liver cancer with a poor prognosis. Amino acid metabolism has been found to alter in cancers and contributes to malignant progression. However, the asparagine metabolism status and relevant mechanism in HCC were...

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Bibliographic Details
Main Authors: Jianguo Bai, Ruifeng Tang, Keyu Zhou, Jialei Chang, Hongyue Wang, Qixin Zhang, Jiahui Shi, Chao Sun
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Medical Genomics
Subjects:
Hepatocellular carcinoma
Asparagine metabolism
Tumor microenvironment
DNA damage response
GOT2
Online Access:https://doi.org/10.1186/s12920-022-01380-z

Internet

https://doi.org/10.1186/s12920-022-01380-z

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