Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas

Retro-inverso Urokinase Receptor Antagonists for the Treatment of Metastatic Sarcomas

Abstract The development of metastases is a multistep process that requires the activation of physiological and biochemical processes that govern migration, invasion and entry of metastatic cells into blood vessels. The urokinase receptor (uPAR) promotes cell migration by interacting with the Formyl...

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Main Authors: Maria Vincenza Carriero, Katia Bifulco, Vincenzo Ingangi, Susan Costantini, Giovanni Botti, Concetta Ragone, Michele Minopoli, Maria Letizia Motti, Domenica Rea, Giosuè Scognamiglio, Gerardo Botti, Claudio Arra, Gennaro Ciliberto, Antonello Pessi
Format: Article
Language:English
Published: Nature Portfolio 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01425-9

Internet

https://doi.org/10.1038/s41598-017-01425-9

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