Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis

Grape seed proanthocyanidin extract protects lymphocytes against histone-induced apoptosis

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape seed proanthocyanidin extract (GSPE),...

Full description

Bibliographic Details
Main Authors: Ping Chang, Bing Mo, David M. Cauvi, Ying Yu, Zhenhui Guo, Jian Zhou, Qiong Huang, Qitao Yan, Guiming Chen, Zhanguo Liu
Format: Article
Language:English
Published: PeerJ Inc. 2017-03-01
Series:PeerJ
Subjects:
Grape seed proanthocyanidin extract
Lymphocyte apoptosis
Mitochondrial injury
Histones
Reactive oxygen species
Online Access:https://peerj.com/articles/3108.pdf

Internet

https://peerj.com/articles/3108.pdf

Similar Items