Optogenetic activation of superior colliculus neurons suppresses seizures originating in diverse brain networks

Optogenetic activation of superior colliculus neurons suppresses seizures originating in diverse brain networks

Because sites of seizure origin may be unknown or multifocal, identifying targets from which activation can suppress seizures originating in diverse networks is essential. We evaluated the ability of optogenetic activation of the deep/intermediate layers of the superior colliculus (DLSC) to fill thi...

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Bibliographic Details
Main Authors: Colin Soper, Evan Wicker, Catherine V. Kulick, Prosper N’Gouemo, Patrick A. Forcelli
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Neurobiology of Disease
Subjects:
Absence epilepsy
Temporal lobe epilepsy
Generalized epilepsy
Rat
Channelrhodopsin-2
Partial seizure
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115301145

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http://www.sciencedirect.com/science/article/pii/S0969996115301145

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