Preliminary study showing no association between G238A (rs361525) tumor necrosis factor-α (TNF-α) gene polymorphism and its serum level, hormonal and biochemical aspects of polycystic ovary syndrome

Preliminary study showing no association between G238A (rs361525) tumor necrosis factor-α (TNF-α) gene polymorphism and its serum level, hormonal and biochemical aspects of polycystic ovary syndrome

Abstract Background Polycystic ovary syndrome (PCOS) is the main cause of female infertility. Interactions among genetic, biochemical, and immunological factors can affect the pathogenesis of PCOS. As a proinflammatory cytokine, tumor necrosis factor-α (TNF-α) plays an important role in this regard....

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Bibliographic Details
Main Authors: Fahimeh Kordestani, Sahar Mazloomi, Yousef Mortazavi, Saeideh Mazloomzadeh, Mojtaba Fathi, Haleh Rahmanpour, Abolfazl Nazarian
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Medical Genetics
Subjects:
Polycystic ovary syndrome (PCOS)
Tumor necrosis factor-alpha (TNF-α)
Hormone profile
Polymorphism
Polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP)
Online Access:http://link.springer.com/article/10.1186/s12881-018-0662-1

Internet

http://link.springer.com/article/10.1186/s12881-018-0662-1

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