Chimeric virus-like particles presenting tumour-associated MUC1 epitope result in high titers of specific IgG antibodies in the presence of squalene oil-in-water adjuvant: towards safe cancer immunotherapy

Chimeric virus-like particles presenting tumour-associated MUC1 epitope result in high titers of specific IgG antibodies in the presence of squalene oil-in-water adjuvant: towards safe cancer immunotherapy

Abstract Background Immunotherapy is emerging as a powerful treatment approach for several types of cancers. Modulating the immune system to specifically target cancer cells while sparing healthy cells, is a very promising approach for safer therapies and increased survival of cancer patients. Tumou...

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Bibliographic Details
Main Authors: Mirosława Panasiuk, Karolina Zimmer, Anna Czarnota, Magdalena Narajczyk, Grażyna Peszyńska-Sularz, Milena Chraniuk, Lilit Hovhannisyan, Sabina Żołędowska, Dawid Nidzworski, Anna J. Żaczek, Beata Gromadzka
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Journal of Nanobiotechnology
Subjects:
Cancer immunotherapy
Cancer vaccines
VLPs
Bioengineered nanostructures
MUC1
Online Access:https://doi.org/10.1186/s12951-022-01357-1

Internet

https://doi.org/10.1186/s12951-022-01357-1

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