Antimicrobial and Antiproliferative Activities and Enzyme Binding Affinity of Xanthen-3-one Derivatives

Antimicrobial and Antiproliferative Activities and Enzyme Binding Affinity of Xanthen-3-one Derivatives

Ten biologically active derivatives of 2,6,7-trihydroxyxanthen-3-one, previously synthesized and characterised, were investigated for their in vitro antimicrobial and antiproliferative activity. Compounds were tested on three bacteria, Staphylococcus aureus, Bacillus subtilis and Escherichia coli, a...

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Bibliographic Details
Main Authors: Elma Veljović, Anja Harej, Marko Klobučar, Sandra Kraljević Pavelić, Selma Špirtović-Halilović, Amar Osmanović, Samija Muratović, Mirsada Salihović, Davorka Završnik
Format: Article
Language:English
Published: Croatian Society of Chemical Engineers 2022-03-01
Series:Kemija u Industriji
Subjects:
xanthenes
antibacterial and antifungal activity
induction of cell death
enzyme binding modes
docking study
bioavailability prediction
Online Access:http://silverstripe.fkit.hr/kui/assets/Uploads/2-131-140-KUI-03-04-2022.pdf

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http://silverstripe.fkit.hr/kui/assets/Uploads/2-131-140-KUI-03-04-2022.pdf

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