Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis

Hypoxia-treated adipose mesenchymal stem cell-derived exosomes attenuate lumbar facet joint osteoarthritis

Abstract Background Lumbar facet joint osteoarthritis (LFJ OA) is a common disease, and there is still a lack of effective disease-modifying therapies. Our aim was to determine the therapeutic effect of hypoxia-treated adipose mesenchymal stem cell (ADSC)-derived exosomes (Hypo-ADSC-Exos) on the pro...

Full description

Bibliographic Details
Main Authors: Jinyun Zhao, Yi Sun, Xiaolong Sheng, Jiaqi Xu, Guoyu Dai, Rundong He, Yuxin Jin, Zhide Liu, Yong Xie, Tianding Wu, Yong Cao, Jianzhong Hu, Chunyue Duan
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Molecular Medicine
Subjects:
Adipose mesenchymal stem cells
Hypoxia-treated ADSC-derived exosomes
Lumbar facet joint osteoarthritis
Subchondral bone
Online Access:https://doi.org/10.1186/s10020-023-00709-3

Internet

https://doi.org/10.1186/s10020-023-00709-3

Similar Items