Brain white matter shape changes in amyotrophic lateral sclerosis (ALS): a fractal dimension study.

Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder. Current diagnosis time is about 12-months due to lack of objective methods. Previous brain white matter voxel based morphometry (VBM) studies in ALS reported inconsistent results. Fractal dimension (FD) has succes...

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Bibliographic Details
Main Authors: Venkateswaran Rajagopalan, Zao Liu, Didier Allexandre, Luduan Zhang, Xiao-Feng Wang, Erik P Pioro, Guang H Yue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3767806?pdf=render